SureSleep, 120g Powder - DoNotage

How It Works: The Science of Sulforaphane & Cellular Defense

Aging isn’t just about getting older, it’s about the gradual breakdown of your body’s internal defense systems.

One of the most important protective mechanisms your body relies on is the Nrf2 pathway. This pathway is a cellular switch that controls over 200 genes involved in detoxification, antioxidant activity, inflammation response, and long-term health.

But as we age, the Nrf2 pathway becomes less responsive. That means more oxidative stress, more inflammation, and less ability to defend and repair. That’s where sulforaphane comes in.

1) Sulforaphane Activates the Nrf2 Pathway – Your Body’s Master Defense System

Sulforaphane is a natural compound found in cruciferous vegetables like broccoli. When activated by the enzyme myrosinase, it helps trigger the Nrf2 pathway, empowering your cells to fight oxidative stress, remove toxins, and reduce inflammation throughout the body.

2) SulforaBoost® Provides Both Essential Components — Glucoraphanin & Myrosinase

Most sulforaphane supplements fall short, they leave out myrosinase, the enzyme needed to activate sulforaphane. Without it, your body can’t make use of the sulforaphane precursor, glucoraphanin. SulforaBoost® includes both, ensuring your body can naturally produce the active compound when and where it’s needed most.

3) Sulforaphane Supports Multiple Systems at Once

Sulforaphane has been shown in research to benefit nearly every system in the body:

• Cellular Detoxification – Stimulates enzymes that eliminate harmful toxins and pollutants.*
• Antioxidant Defense – Boosts production of glutathione, your body’s master antioxidant.*
• Cognitive Health – Helps protect brain cells from oxidative stress and inflammation.*
• Heart & Vessel Health – Supports healthy circulation and reduces cardiovascular stress.*
• Immune Function – Enhances immune system balance and defense under chronic stress.*
• Skin & Cellular Protection – Defends against UV and environmental skin damage.*
• Hormonal Health – Helps detoxify excess estrogens and maintain hormonal balance.*

At DoNotAge.org, we lead the research so you can take charge of your health. SulforaBoost® is a research-leading formula, developed with purity, stability, and bioactivation in mind. Every batch is rigorously tested and contains active myrosinase ensuring your body gets the real, effective sulforaphane that researchers around the world depend on.

1) SureSleep™ Helps Rebuild Healthy Sleep-Wake Cycles

SureSleep™ is formulated with research-leading ingredients like Magnesium Glycinate, Apigenin, and L-Theanine. Natural compounds known to support the calming neurotransmitters that drive healthy sleep patterns.

By promoting GABAergic activity and easing nighttime cortisol levels, SureSleep™ helps the body naturally transition into deep, restorative sleep without the grogginess or dependency common to synthetic sleep aids.

2) SureSleep™ Targets the Root Causes of Sleep Disruption

Instead of masking sleep issues like many over-the-counter solutions, SureSleep™ addresses them at their origin:

• Reduces stress signals that delay sleep onset*
• Balances neurotransmitter pathways critical for relaxation and mood*
• Supports deeper sleep stages essential for cellular and cognitive recovery*

Every ingredient is carefully selected to work with, not against your body’s natural circadian rhythms.

3) SureSleep™ Supports Full-System Recovery Overnight

High-quality sleep impacts far more than energy levels.Research shows that restorative sleep is essential for:

• Brain Detoxification – Promotes clearance of metabolic waste from brain cells, protecting cognitive function*
• Cellular Repair – Supports the body’s natural repair of muscle, bone, and connective tissue overnight*
• Hormonal Balance – Regulates cortisol, melatonin, and other hormones critical to stress resilience and metabolism*
• Immune Strengthening – Helps reinforce immune surveillance during the deep sleep stages*
• Metabolic Health – Supports glucose regulation and mitochondrial efficiency tied to nighttime recovery*

At DoNotAge.org, we lead the research so you can reclaim your natural health from the inside out.

SureSleep™ is a science-leading formulation, developed with bioavailability, purity, and clinical relevance in mind so you can experience deeper rest and stronger resilience night after night.

BENEFITS OF SURESLEEP

• ✅ Promotes Deep Sleep – Encourages full-spectrum sleep cycles for true recovery and vitality.*
• ✅ Calms the Mind and Nervous System – Eases stress pathways to support natural relaxation and ease into sleep.*
• ✅ Strengthens Overnight Recovery – Fuels the cellular and neurological repair processes that happen while you sleep.*
• ✅ Supports Stress and Hormonal Balance – Helps regulate cortisol and promote a healthier daily rhythm.*
• ✅ Enhances Cognitive and Immune Function – Improves overnight brain detox and reinforces immune health during sleep.*

PRODUCT DETAILS

• ✅ Bioavailable Sleep Support – Features Magnesium Glycinate, L-Theanine, and Apigenin in highly absorbable forms.
• ✅ Naturally Sourced Ingredients – Derived from non-GMO botanical sources with no artificial fillers or additives.
• ✅ Scientifically Tested Formulation – Each batch is rigorously verified for purity, potency, and consistency.
• ✅ Vegan, Non-GMO, and Allergen-Free – Formulated without animal products, synthetic preservatives, or major allergens.
• ✅ Trusted by Health Researchers – Ingredients chosen based on clinical insights into sleep, brain health, and stress recovery.*
• ✅ Certified by DoNotAge.org – Held to the highest standards of research integrity and ingredient quality.

The Science Behind SureSleep™

At DoNotAge.org, we are a Health Research Organisation dedicated to advancing real, research-led health solutions, not marketing fads. Our mission is to identify the most effective, biologically relevant ingredients found in nature to support the body’s core systems of repair, regulation, and resilience.

SureSleep™ was developed in response to one of the most overlooked yet essential pillars of long-term health: sleep. While many sleep aids focus on sedation or surface-level effects, SureSleep™ works with the body’s natural rhythms to help restore deep, restorative sleep, where true recovery and repair begin.

This formula combines bioavailable Magnesium Glycinate, calming L-Theanine, and plant-derived Apigenin to support the pathways responsible for stress reduction, sleep onset, and overnight cellular renewal. Each ingredient was selected based on clinical insights into how the nervous system, brain, and hormonal cycles regulate sleep and resilience.

We’re not chasing quick fixes or hype. We’re building protocols the science supports so your body can access the quality of rest it was designed for.

This is SureSleep™. And this is how science restores recovery.

The Benchmark for Scientific Purity

At DoNotAge.org, purity isn’t a claim, it’s a commitment backed by in-house validation and ongoing research partnerships.

Scientists and health researchers across the globe trust our ingredients because we control every step of the process from sourcing to analysis to release. Every ingredient in SureSleep™ is tested for potency, consistency, and biological activity to ensure it supports your body exactly as intended.

We never rely on supplier guarantees or assumptions. We verify, analyze, and test against the highest internal standards to ensure what we deliver is not just clean but clinically meaningful.

This commitment to quality is why experts in neurology, circadian biology, and stress recovery continue to choose DoNotAge.org as their trusted source. With SureSleep™, they know exactly what they’re working with: safe, active, and biologically aligned with the body's natural repair systems.

What the Science Says

Our science-led approach is driven by what the evidence shows, not what’s trending. Studies and clinical insights into SureSleep™’s core ingredients suggest the following benefits:

• ✅ Promotes Healthy Sleep Architecture – Magnesium Glycinate and Apigenin help regulate neurotransmitters and promote deeper stages of sleep where full-body repair occurs.*
• ✅ Supports Cognitive Recovery – Sleep plays a critical role in clearing neurotoxins and restoring memory consolidation, helping the brain reset and renew overnight.*
• ✅ Helps Balance Cortisol and Melatonin – Chronic stress and disrupted rhythms can throw off your hormonal cycles. SureSleep™ helps regulate them naturally.*
• ✅ Strengthens Immune Activity During Sleep – Deep sleep boosts immune surveillance and cellular repair critical to daily resilience.*
• ✅ Encourages Full-Body Cellular Repair – Sleep is when tissues, organs, and systems rebuild. SureSleep™ helps your body get the uninterrupted rest needed to do exactly that.*

A Scientific Breakthrough in Longevity

At DoNotAge.org, we collaborate with leading scientists across fields such as neurology, circadian biology, and human resilience to formulate ingredients that make a measurable difference. SureSleep™ is the result of this research-led mission.

Emerging studies continue to confirm the essential role of deep sleep in long-term health outcomes, everything from brain and immune health to emotional balance and mitochondrial function. Our formulation was developed with these insights in mind: not to override the body’s systems, but to support them at the root.

Because when your sleep improves, everything improves: recovery, energy, mood, clarity, and resilience.

Our goal isn’t just to help you rest, it's to help your body restore itself, night after night.

Scientific References & Studies:

• The Effects of Rhodiola rosea L. Extract on Anxiety, Stress, Cognition and Other Mood Symptoms
• Stress management and the role of Rhodiola rosea
• Rhodiola rosea versus sertraline for major depressive disorder
• Salidroside Induces Apoptosis in Human Gastric Cancer Cells via the Downregulation of ENO1/PKM2/GLUT1 Expression
• Valerian Root in Treating Sleep Problems and Associated Disorders—A Systematic Review and Meta-Analysis
• Effect of valepotriates (valerian extract) in generalized anxiety disorder
• Effect of tart cherry juice (Prunus cerasus) on melatonin levels and enhanced sleep quality

SureSleep™ is part of our greater mission to deliver the most effective, research-led health solutions available today. With clinically relevant ingredients, verified purity, and a formulation designed to work in sync with your body’s natural rhythms, SureSleep™ supports deep restorative sleep and overnight recovery where true resilience begins.

Join us in advancing a healthier, more balanced future. Try SureSleep™ today and experience the science of full-body renewal through better sleep.

SureSleep™ – Restorative Sleep and Overnight Resilience

At DoNotAge.org, we don’t follow sleep trends, we lead health science to address the root causes of sleep disruption and stress-driven exhaustion. SureSleep™ is formulated with clinically relevant ingredients that support the body’s natural ability to unwind, recover, and repair during sleep.

Unlike conventional sleep aids that rely on sedation or synthetic melatonin, SureSleep™ features a synergistic blend of six research-leading ingredients, each selected for its role in supporting neurological calm, circadian balance, and overnight cellular repair.

One of these, Prunus Cerasus (tart cherry), contains natural levels of melatonin, the hormone that regulates the sleep-wake cycle. In the melatonin chemical structure, you’ll see how this compound interacts with the brain’s signaling systems to initiate and maintain restful sleep. SureSleep™ supports your body's production and regulation of melatonin through natural pathways, without the overstimulation or dependency risks common to synthetic alternatives.

Each 4g serving includes:

• Magnesium Glycinate – Supports nervous system relaxation and helps calm evening cortisol levels*
• Magnesium Citrate – Helps regulate neurotransmitter activity and promotes sleep onset*
• L-Tryptophan – An essential amino acid involved in serotonin and melatonin synthesis*
• Prunus Cerasus Extract – A natural source of melatonin and anthocyanins that support circadian rhythm*
• L-Theanine – Enhances alpha brain waves and supports a calm, focused transition into sleep*
• Natural Cherry Flavor – Adds a gentle, palatable taste to the evening routine*

Scientific research supports that these compounds work synergistically to:

• ✅ Promote Deep Sleep Cycles – Support full-spectrum sleep phases that allow for neurological and physical recovery*
• ✅ Balance the Sleep-Wake Rhythm – Encourage consistent melatonin signaling and circadian alignment*
• ✅ Ease Stress and Calm the Mind – Reduce evening hyperactivity in the brain and help the body shift into parasympathetic mode*
• ✅ Support Overnight Recovery – Enable cellular repair, hormone regulation, and immune system optimization during sleep*
• ✅ Improve Next-Day Energy and Mental Clarity – Help you wake up feeling truly restored without grogginess or crash*

Not all sleep solutions are created equal. SureSleep™ is built for biological compatibility, purity, and effectiveness without the fillers, shortcuts, or synthetic additives common in the supplement space.

At DoNotAge.org, we are committed to delivering the most scientifically advanced health solutions in the world. SureSleep™ is a reflection of that mission; natural, targeted, and built to restore your body’s most essential recovery system: sleep.

The DoNotAge.org Quality Guarantee

This product comes with the DoNotAge.org Quality Guarantee. We proudly guarantee purity and quality from our facility to your home, no matter where you live.

✅ Produced to GMP and ISO9001 Standards – Ensuring the highest levels of manufacturing excellence.*

✅ Science-Led & Rigorously Tested – Formulated for superior effectiveness and safety.*

✅ Full Instructions Included – Your order comes with easy-to-follow guidelines for optimal results.*

✅ 100% Vegan & Clean – Free from unnecessary additives, making it suitable for all dietary preferences.*

At DoNotAge.org, we’re committed to more than just providing ingredients, we're building a healthier future through real science. SureSleep™ is part of that mission: a clinically informed, high-integrity solution designed to support your body’s natural defense systems every day.

World-Leading Purity & Scientifically Verified Formulas

At DoNotAge.org, we are a Health Research Organisation, not a supplement brand. Our mission is to investigate, develop, and deliver ingredients of unmatched purity, backed by research and formulated for real biological outcomes, not marketing claims.

• Active Sulforaphane Formula – Combines glucoraphanin and myrosinase to ensure real sulforaphane activation in the body.*
• GMP & ISO9001 Certified – Manufactured to the highest global standards for quality, safety, and consistency
• In-House Verified – Every batch is tested internally for molecular weight, peptide concentration, and absence of contaminants
• Used in Scientific Research – Our formulations are selected by researchers and institutions for use in health-focused studies
• Full Label Transparency – What’s listed is what you get. No fillers, no fluff just clean, functional ingredients your body recognises

At DoNotAge.org, we don’t follow trends, we define what research-led health looks like. No shortcuts. No guesswork. Just evidence-driven solutions designed for real structural results.

DoNotAge.org Quality Guarantee

This product comes with the DoNotAge.org Quality Guarantee, ensuring uncompromised purity and potency from our facility to your doorstep, no matter where you live.

• ✅ GMP & ISO9001 Certified – Manufactured under the highest standards.
• ✅ Third-Party Lab Tested – Verified for purity, potency, and safety.
• ✅ Bioavailable & Effective – Every ingredient is carefully curated for maximum absorption and longevity benefits.
• ✅ Vegan & Allergen-Free – No fillers, additives, or unnecessary ingredients.

Full instructions for use are included with every order.

Join us in our mission to revolutionize health and longevity, because living longer is only worth it when you're living better.

Committed to Extending Healthy Lifespans

At DoNotAge.org, our mission is simple yet profound:

To extend healthy lifespans for as many people as possible.

We believe that longevity should be accessible to everyone, not just the elite. That’s why we provide the world’s purest, research-leading supplements at the lowest possible cost so more people can benefit from the latest breakthroughs in health and aging. There's a reason our longevity ingredients are actually used in world-leading studies, and by world renown longevity experts.

We work hand-in-hand with leading scientists, longevity researchers, and medical professionals to ensure that every product we offer is at the cutting edge of human health and performance. Our advisory board includes decorated longevity scientists and medical experts, ensuring that our formulations are backed by the latest research and clinical evidence.

We aren’t a supplement company, we are a global movement of over 200,000 individuals dedicated to extending and improving human health. With a growing community spanning the United States, Canada, Australia, Germany, and beyond, we are united in a shared mission: helping people live longer, healthier, and more vibrant lives.

Why We Do What We Do

Most supplement brands focus on profit. We focus on science. We are not here to maximize profits. We are here to maximize your health and longevity.

• ✅ Our Commitment to Research – We actively collaborate with scientists, researchers, and anti-aging experts to stay ahead of the latest breakthroughs.
• ✅ Making Longevity Accessible – We keep our prices as low as possible so that more people can benefit from life-extending science.
• ✅ No Compromises on Quality – Every batch of Pure Berberine meets the strictest testing and safety standards in the industry.

At DoNotAge.org, we are a Health Research Organisation, our profits fund longevity studies and conduct our own research, ensuring that our ingredients are actually used in clinical trials.

Product & Usage

What is SureSleep™, and how does it work?

SureSleep™ is a natural, research-led sleep support formula developed by DoNotAge.org. It combines clinically relevant doses of Magnesium Glycinate, Magnesium Citrate, L-Tryptophan, L-Theanine, and Prunus Cerasus (tart cherry) ingredients shown to support the body’s natural sleep-wake rhythm, calm the nervous system, and promote deep, restorative sleep. Rather than relying on synthetic melatonin or sedatives, SureSleep™ works with your body’s own biology to enhance overnight recovery and resilience.*

How should I take SureSleep™?

Mix one serving (4g) with water and take approximately 30–60 minutes before your desired bedtime. For best results, use consistently each evening as part of a wind-down routine. Avoid taking it alongside caffeine or other stimulants in the evening hours.

What is the recommended daily dosage?

One 4g serving per day is recommended. This provides optimal levels of all active ingredients to support healthy sleep quality, cognitive recovery, and overnight hormonal balance.*

When is the best time to take SureSleep™?

SureSleep™ is best taken in the evening, about 30 to 60 minutes before bedtime. The ingredients are formulated to support natural melatonin production, reduce nighttime stress signals, and help ease the body into sleep.*

Is SureSleep™ safe to take every night?

Yes. SureSleep™ is designed for daily, long-term use. It is non-habit-forming, vegan, non-GMO, and free from common allergens. Each batch is rigorously tested for purity, consistency, and effectiveness in accordance with DoNotAge.org’s research standards.

What age should I start taking SureSleep™?

SureSleep™ is suitable for adults of any age who want to improve sleep quality, reduce stress, and support overnight recovery. It may be especially beneficial for individuals experiencing disrupted sleep due to stress, hormonal shifts, or circadian rhythm imbalances.*

Quality & Purity

What Makes SureSleep™ Different?

• ✔ Multi-Compound Sleep Formula – Includes research-led doses of Magnesium Glycinate, Magnesium Citrate, L-Tryptophan, L-Theanine, and Prunus Cerasus to support the full sleep cycle.*
• ✔ Natural Melatonin Support – Prunus Cerasus (tart cherry) is a natural source of melatonin, promoting circadian balance without synthetic melatonin.*
• ✔ Plant-Based & Vegan Friendly – Made with clean, non-GMO, plant-derived ingredients with no animal byproducts.
• ✔ Formulated for Absorption – Designed to deliver active compounds efficiently with optimal bioavailability and synergy.*
• ✔ Trusted by Health Researchers – Ingredients selected based on current research in sleep science, brain health, and stress recovery.
• ✔ Simple, Daily Use – Easy to take as part of your nightly routine with water, 30–60 minutes before bedtime.

How do you ensure the purity of SureSleep™?

Every batch of SureSleep™ undergoes rigorous in-house testing as well as independent third-party verification to confirm identity, potency, and purity. Certificates of analysis are available upon request for full transparency and scientific confidence.

Are there any fillers or artificial additives in SureSleep™?

No. SureSleep™ contains only active, clinically relevant ingredients along with natural cherry flavor for taste. There are no hidden fillers, synthetic preservatives, or unnecessary additives.

Where do you source your ingredients from?

Each ingredient in SureSleep™ is sourced from trusted suppliers that meet our strict GMP and ISO9001-certified standards. All ingredients are selected for their purity, traceability, and biological relevance to sleep and neurological health.

Is SureSleep™ suitable for vegans?

Yes. SureSleep™ is 100% vegan and free from animal products, allergens, gluten, and artificial compounds. It is formulated with integrity and transparency in alignment with DoNotAge.org’s clean-label standards.

How should I store SureSleep™?

Store SureSleep™ in a cool, dry place away from heat and direct sunlight. While refrigeration is not required, it may be used for added freshness if preferred.

How does DoNotAge.org store SureSleep™ before shipping?

All SureSleep™ formulations are stored in clean, temperature-controlled environments that are dark, dry, and fully compliant with GMP and ISO9001 guidelines. This ensures stability, potency, and freshness from the moment it is produced until it reaches you.

Additional Questions

Should SureSleep™ be taken separately from medication?

SureSleep™ is generally safe for most healthy adults. However, because it contains ingredients that may influence neurotransmitter activity, stress response, and melatonin production, we recommend consulting your healthcare professional before use if you are taking prescription medications, especially those related to sleep, mood, or neurological function.*

Is SureSleep™ safe to take while pregnant or nursing?

There is limited research on the use of SureSleep™ ingredients such as L-Tryptophan, L-Theanine, and tart cherry extract during pregnancy or breastfeeding. Please consult your healthcare provider before using SureSleep™ if you are pregnant or nursing.*

Can I give SureSleep™ to my child?

SureSleep™ is formulated for adult use only. If you are considering sleep support for a child or adolescent, please speak with a qualified healthcare practitioner.

Where can I find more research on SureSleep™?

You can explore scientific literature and ingredient references related to sleep, circadian health, and neurological recovery on our Science & Research page, or contact our support team for additional information.